Anti N-methyl-d-aspartate (NMDA) ReceptorEncephalitis with Frustrated Diagnosis Course: ACase report
نویسندگان
چکیده
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare disease with uncertain etiology and pathogenesis that affects young women. Its diagnosis can be delayed because of the nonspecific neuropsychiatric symptoms in the foreground. This article describes the details of a recent complicated case of a patient with this condition which is related to an ovarian teratoma. Correct diagnostic and prompt treatment of antiNMDA receptor encephalitis remains a serious clinical challenge due to its unspecific manifestations and varying response to treatments. The information will be of interest to clinicians working with encephalitis patients.
منابع مشابه
Anti-N-Methyl-D-Aspartate-Receptor Encephalitis, a Challenge for Neurologists or a Chameleon for Psychiatrists: A Case Report
Anti-N-Methyl-D-Aspartate-Receptor (NMDA-R) encephalitis is a new autoimmune disorder, often paraneoplastic in nature, presenting with complex neuropsychiatric symptoms. Diagnosed serologically, this disorder is often responsive to immunosuppressant treatment. We here in report the case of a 56-year-old man with anti NMDA-R encephalitis presenting initially with disorientation and hallucinati...
متن کاملO 17: Childhood Anti-NMDA Receptor Encephalitis
Anti N-methyl-D-aspartate receptor (NMDR) encephalitis has been recognized as the most frequent autoimmune encephalitis in children after acute demyelinating encephalomyelitis (ADEM).However due to the variable the variable clinical presentation, the paucity of specific finding on standard laboratory and radiological investigation remains under recognized. First discribed in 2005, most commonly...
متن کاملThe effect of morphine dependence on expression of hippocampal N-methyl-D-aspartate receptor subunits in male rats
Introduction: N-methyl-D-aspartate (NMDA) receptors play a pivotal role in the development of tolerance and physical dependence to opiates. Activation of NMDA receptors involves the induction of long term potentiation (LTP) in hippocampus. Our previous study suggested that chronic oral administration of morphine enhanced NMDA dependent LTP in the CA1 area of hippocampal slices of rats. The p...
متن کاملAnti-NMDA receptor encephalitis presenting with imaging findings and clinical features mimicking Rasmussen syndrome
BACKGROUND Antibody mediated anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a recently reported diagnosis of clinical importance. Recognition of the syndrome, especially in pediatric populations, is difficult and often undiagnosed and/or confused with neurological disorders with similar clinical features. RESULTS We report a case of an 11 year old female with explosive-onset epilep...
متن کاملAnti-N-Methyl-D-Aspartate (Anti-NMDA) Receptor Encephalitis as the Initial Presentation of Small Cell Carcinoma of the Lung in a Middle-Aged Man
This case report describes a previously healthy 55 year-old man with unremarkable family and medical history presenting with Cotard delusion, unintentional weight loss, and psychomotor agitation requiring sedation. Testing revealed CSF leukocytosis and erythrocytosis, leading to a preliminary diagnosis of viral herpes encephalitis. As the patient continued to deteriorate, anti-NMDA receptor ant...
متن کامل